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Post details: R-Hyper CVAD
11:09:19 pm, Categories: Treatments, 1769 words
I'll be taking R-Hyper CVAD, which will be administered in the hospital for 4-5 days, every 3 weeks, for 6-8 cycles.
R-Hyper CVAD (R-HCVAD/-Mtx AraC)
Cycle A Breaks down for me as:
Antibiotics - given daily
Cycle B for me is:
The standard info that I've gotten off the web for R-Hyper CVAD is:
R-yper CVAD (B cycle)
NAME: methotrexateBRAND NAMES: Rheumatrex, Trexall
GENERIC AVAILABLE: yes
PREPARATIONS: Injectable: 25mg/ml; Tablet: 2.5mg (Rheumatrex), and 5, 7.5, 10 and 15 mg (Trexall).
STORAGE: Store between 59 and 77degrees F in a sealed container, avoid light.
PRESCRIBED FOR: Methotrexate is used for cancer treatment generally in higher doses than for other uses, and is often administered intravenously or intramuscularly. Methotrexate is used to treat psoriasis, an inflammatory skin disease, as well as the arthritis that occurs in 10 percent of these patients (psoriatic arthritis). It is also used to treat active rheumatoid arthritis in adults and children. It is also used to treat other rheumatic diseases, including polymyositis and systemic lupus erythematosus. Methotrexate has been used to induce miscarriage in patients with ectopic pregnancy.
DOSING: May be taken with or without food. For rheumatoid arthritis and psoriasis, the dose of methotrexate is given WEEKLY, whether by injection or orally. For psoriasis, the weekly dose is often divided into three doses given at 12 hour intervals each week. This has been shown to be more effective, as it relates to the natural growth cycling of the skin.
DRUG INTERACTIONS: Because methotrexate can cause serious liver disease, patients with alcoholism or liver disease should not receive it. Patients should curtail alcohol consumption while taking methotrexate. Methotrexate can suppress the body's immunity. Therefore, any symptoms of infection should be reported to the doctor. Patients with underlying immune deficiency diseases should not receive methotrexate. A dry, non-productive cough can be a result of a rare lung toxicity. Methotrexate can impair fertility, decrease sperm count and cause menstrual dysfunction. Safety and effectiveness has not been established in children.
PREGNANCY: Methotrexate should not be used in pregnancy, as it can be toxic to the embryo and can cause fetal defects and spontaneous abortion (miscarriage). It should be discontinued prior to conception if used in either partner. Male patients should stop taking methotrexate at least 3 months prior to a planned conception and females should discontinue use for at least one ovulatory cycle before conception.
SIDE EFFECTS: Methotrexate can be well tolerated, but also can cause severe toxicity which is usually related to the dose taken. The most frequent reactions include mouth sores, stomach upset, and low white blood counts. Methotrexate can cause severe toxicity of the liver and bone marrow, which require regular monitoring with blood testing. It can cause headache and drowsiness, which may resolve if the dose is lowered. Methotrexate can cause itching, skin rash, dizziness, and hair loss. A dry, non-productive cough can be a result of a rare lung toxicity.
GENERIC NAME: CYTARABINE - INJECTION (sye-TAIR-uh-bean)BRAND NAME(S): Cytosar-U, Tarabine PFS
WARNING: This medication will be given where you can be closely monitored by your doctor because serious (rarely fatal) blood disorders (e.g., anemia, bone marrow suppression) have been caused by this medication. Liver problems may also develop. Notify your doctor immediately if you develop fever, unusual fatigue, nausea, vomiting, diarrhea, persistent sore throat, easy bruising or bleeding, abdominal or stomach pain, dark urine, yellowing eyes or skin, or mouth sores.
USES: Cytarabine is one of a large group of drugs known as "antineoplastics"; these drugs are also known as cancer drugs, chemotherapy, or "chemo". They are used in the treatment of various cancers to slow or stop the growth of cancer cells. A combination of different types of cancer drugs will often be used to achieve better results and minimize side effects.
HOW TO USE: This is a potent medication. Use it exactly as prescribed. Unless your doctor instructs you otherwise, drink plenty of fluids while using this medication. This helps your kidneys to remove the drug from your body and avoid some of the side effects. Do not stop using this medication, even if you feel nauseated or experience vomiting.
SIDE EFFECTS: Nausea, vomiting, loss of appetite, headache, itching, freckling, diarrhea, dizziness are common side effects. Using the drug on an empty stomach may help to relieve vomiting. Changes in diet such as eating several small meals or limited activity may help lessen some of these effects. In some cases, drug therapy may be necessary to prevent or relieve nausea and vomiting. Temporary hair loss is another common side effect. Normal hair growth should return after treatment has ended. Contact your doctor without delay if you experience any of the following symptoms: fever, chills, painful or difficult urination, chest pain, heartburn, difficulty swallowing, easy bruising or bleeding, black or tarry stools, blood in urine or stools, pinpoint red spots on the skin, joint/back/side pain, swollen feet or lower legs, sores in the mouth or on the lips, yellowing of the eyes or skin, dark urine, shortness of breath, bone or muscle pain, severe stomach pain. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Tell your doctor your medical history, especially of: kidney or liver problems, gout, infections, allergies (especially drug allergies). Contraceptive (birth control) measures are recommended for use in men and women while using this medication. A preservative (benzyl alcohol) which may be found in this product or in the liquid used to mix this product (diluent) can infrequently cause serious problems (sometimes death), if given in large amounts (more than 100 mg/kg daily) to an infant during the first months of life (neonatal period). The risk is also greater with low birth weight infants. Symptoms include sudden gasping, low blood pressure, or a very slow heartbeat. Report these symptoms to the doctor immediately should they occur. If possible, a preservative-free product should be used when treating neonates. Cytarabine is not recommended for use during pregnancy. Consult your doctor for details. It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription drugs you may use, especially of: medicines used for gout. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
NOTES: This medication can lower your body's ability to fight an infection. Notify your doctor if you develop any signs of an infection such as fever, sore throat, rash or chills. Avoid touching your eyes or inside your nose without first washing your hands. Use caution with sharp objects like safety razors or nail cutters and avoid activities such as contact sports in order to lower the chance of getting cut, bruised or injured. Do not have immunizations/vaccinations without consent of your doctor, and avoid contact with people who have recently received oral polio vaccine. Regular doctor visits are important. Frequent blood tests will be done to monitor therapy.
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